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Filtered Search Results
Medchemexpress LLC Afatinib impurity 4 | 74874-10-5 | MFCD08458426 | 250mg
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Afatinib impurity 4 is an impurity of Afatinib (HY-10261)
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Medchemexpress LLC BIX-01294 | 935693-62-2 | 98.4% | 490.64 | 250 MG
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BIX-01294 is a reversible and highly selective G9a and GLP Histone Methyltransferase inhibitor, with IC50s of 1.7 μM and 0.9 μM, respectively. It inhibits G9a/GLP by competing for binding with the amino acids N-terminal of the substrate lysine residue. This (1H-1,4-diazepin-1-yl)-quinazolin-4-yl amine derivative induces necroptosis and autophagy and has antitumor activity in recurrent tumor cells.
- Reversible and highly selective G9a and GLP Histone Methyltransferase inhibitor
- Induces necroptosis and autophagy
- Exhibits antitumor activity in recurrent tumor cells
- Inhibits G9a/GLP by competing for binding with amino acids N-terminal of substrate lysine residue
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Medchemexpress LLC N-Carbamoyl-DL-aspartic acid | 923-37-5 | 99.9% | 500 MG
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N-Carbamoyl-DL-aspartic acid (Ureidosuccinic acid) is an endogenous metabolite and a precursor of nucleic acid pyrimidines. This compound is known for its antitumor activities.
- Precursor of nucleic acid pyrimidines.
- Exhibits antitumor activities.
- Demonstrates antitumor activity in a murine Lewis lung carcinoma model.
- Inhibits antitumor activity and toxicity induced by N-phosphonacetyl-L-aspartate (PALA) in animal models.
- Intended for research use only.
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Medchemexpress LLC 3-[4-(6-(3-(dimethylamino)propoxy)benzo[d]oxazol-2-yl)phenoxy]-N,N-dimethylpropan-1-amine | 1219962-49-8 | >98.0% | 397.52 g/mol | C23H31N3O3 | 250MG
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AT791 is a small-molecule inhibitor of Toll-like receptors TLR7 and TLR9 used in research to modulate innate immune signaling. It inhibits TLR7 and TLR9 signaling in human and mouse cell types, prevents DNA-TLR9 interaction in vitro, and has demonstrated activity in mouse challenge models. Supplied as a research-grade powder; verify lot documentation for purity and handling.
- Potent inhibitor of TLR7 and TLR9.
- Demonstrated activity in human and mouse cell types.
- Blocks DNA-TLR9 interaction in vitro.
- Shows efficacy in mouse in vivo challenge models.
- Research-grade powder with >98.0% purity by HPLC.
- Chemical formula C23H31N3O3 and molecular weight ≈397.52 g/mol.
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eMolecules 3680-69-1 | 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine | J & W PharmLab LLC | MFCD01686865 | 153.570 | C6H4ClN3 | 96.000 | Clc1ncnc2[nH]ccc12 | 100g | 499972346
4-Chloro-7H-pyrrolo[2,3-d]pyrimidine | J & W PharmLab LLC | 3680-69-1 | MFCD01686865 | 153.570 | C6H4ClN3 | 96.000 | Clc1ncnc2[nH]ccc12 | 100g | 499972346
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eMolecules 3680-69-1 | 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine | J & W PharmLab, LLC | MFCD01686865 | 153.570 | C6H4ClN3 | 96.000 | Clc1ncnc2[nH]ccc12 | 5g | 249980847
4-Chloro-7H-pyrrolo[2,3-d]pyrimidine | J & W PharmLab, LLC | 3680-69-1 | MFCD01686865 | 153.570 | C6H4ClN3 | 96.000 | Clc1ncnc2[nH]ccc12 | 5g | 249980847
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eMolecules 10070-92-5 | Pyrimidine-5-carboxaldehyde | Combi-Blocks | MFCD03426065 | 108.100 | C5H4N2O | 97.000 | O=Cc1cncnc1 | 25g | 296390765
Pyrimidine-5-carboxaldehyde | Combi-Blocks | 10070-92-5 | MFCD03426065 | 108.100 | C5H4N2O | 97.000 | O=Cc1cncnc1 | 25g | 296390765
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eMolecules 3680-69-1 | 4-chloro-7H-pyrrolo[2,3-d]pyrimidine | Key Organics/BIONET | MFCD01686865 | 153.570 | C6H4ClN3 | 97.000 | Clc1ncnc2[nH]ccc12 | 50mg | 600882981
4-chloro-7H-pyrrolo[2,3-d]pyrimidine | Key Organics/BIONET | 3680-69-1 | MFCD01686865 | 153.570 | C6H4ClN3 | 97.000 | Clc1ncnc2[nH]ccc12 | 50mg | 600882981
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Medchemexpress LLC 4-(2-pyridyldithio)butanoic acid | 250266-79-6 | >98.0% | 229.32 g·mol⁻¹ | C9H11NO2S2 | 250 MG
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Acid-C3-SSPy is a cleavable disulfide linker used as a building block in the synthesis of DBA-DM4, an agent-linker conjugate for antibody-drug conjugates (ADC). It is supplied as a solid research reagent and is intended for laboratory use only.
- Cleavable disulfide linker suitable for ADC synthesis
- Used as a building block in preparing agent-linker conjugates
- Molecular formula: C9H11NO2S2
- Molecular weight: 229.32 g·mol⁻¹
- CAS number: 250266-79-6
- Purity: >98.0%
- Supplied as a 250 mg solid
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Cayman Chemical Stearidonic Acid ethyl ester
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An essential fatty acid in the ω-3 series; an ester of the free acid that is less water soluble, but more amenable for the formulation of stearidonate-containing diets and dietary supplements
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eMolecules Combi-Blocks Inc 1-Methyl-2-oxopyridine-3-boronic acid 250mg 848838776 FA-6752 96 000 1454558-46-3 MFCD23699496 152 940 C6H8BNO3
Combi-Blocks Inc 1-Methyl-2-oxopyridine-3-boronic acid 250mg 848838776 FA-6752 96 000 1454558-46-3 MFCD23699496 152 940 C6H8BNO3
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Medchemexpress LLC AP1867-2-carboxymeth 250mg | 2230613-03-1 | 250 MG
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AP1867-2-(carboxymethoxy) is a synthetic FKBP12(F36V)-directed ligand moiety used as the FKBP12-binding component in dTAG and PROTAC constructs. Supplied as a high-purity solid for research applications, it serves as a building block for targeted protein degradation synthesis and assay development.
- High purity solid (99.88%).
- Molecular weight 693.78 g/mol.
- Molecular formula C38H47NO11.
- Suitable for chemical synthesis of dTAG or PROTAC molecules.
- Available in multiple pack sizes, including 250 mg.
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Medchemexpress LLC Thiabendazole (Standard) | 148-79-8 | 99.9% | 250 MG
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Thiabendazole (Standard) is the analytical standard of Thiabendazole. It is intended for research and analytical applications. Thiabendazole inhibits worm-specific fumarate reductase and has anthelmintic properties. It is for research use only and not sold to patients.
- Serves as a reference standard for assays
- Used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS
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Medchemexpress LLC Lercanidipine (hydrochloride) | 132866-11-6 | 99.93% | 250 MG
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Lercanidipine hydrochloride is a third-generation, lipophilic, brain-penetrant, vascular-selective, and orally active dihydropyridine-calcium channel blocker with a pIC50 of 7.74. It exhibits long-lasting antihypertensive action and offers reno- and neuro-protective effects, and can be used in cardiovascular and neurological research.
- Functions as a dihydropyridine-calcium channel blocker
- Demonstrates long-lasting antihypertensive action
- Provides reno- and neuro-protective effects
- Exhibits anti-oxidant properties
- Possesses anti-inflammatory properties
- Shows anti-apoptotic properties
- Suitable for cardiovascular and neurological research
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Medchemexpress LLC Trimethoprim | 738-70-5 | MFCD00036761 | 100.0% | 250 MG
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Trimethoprim is a bacteriostatic antibiotic that functions as an orally active dihydrofolate reductase inhibitor. It demonstrates effectiveness against a broad spectrum of both Gram-positive and Gram-negative aerobic bacteria, with potential applications in treating various infections.
- Inhibits dihydrofolate reductase (DHFR) activity.
- Effective against Gram-positive and Gram-negative aerobic bacteria.
- Researched for urinary tract infections, Shigellosis, and Pneumocystis pneumonia.
- Inhibits Influenza A virus infection in chick embryos when combined with zinc.
- Molecular weight: 290.32.
- Formula: C14H18N4O3.
- Appearance: Solid, white to off-white.
- Soluble in DMSO (50 mg/mL) and H2O (0.67 mg/mL).
- Induces protein aggregation and heat shock proteins in E. coli cells.
- Shows antibacterial activity in vivo against various bacteria.
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